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How much is Alabama favored to beat Mississippi State by?

Sep 19, 2026; Tuscaloosa, Alabama, USA; Alabama Crimson Tide head coach Kalen DeBoer looks on from the sidelines during the first half against the Florida State Seminoles at Saban Field at Bryant-Denny Stadium. Mandatory Credit: David Leong-Imagn Images

Alabama football opened the week as a four-and-a-half-point favorite over the Mississippi State Bulldogs, according to multiple sportsbooks.

The Crimson Tide and the Bulldogs are both undefeated. Alabama will travel to Starkville to take on Mississippi State in one of the biggest games of the week’s college football slate. Kickoff for the highly anticipated matchup is set for 11 a.m.

The game will be broadcast on ABC. Both teams will be coming off wins over SEC opponents. The Tide beat South Carolina on Saturday, and the Bulldogs defeated a ranked Missouri team.

Alabama defeated Mississippi State 40-17 the last time the two programs played in 2023.

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